Mercedes-Benz E350 Problems

RepairPal has identified the most common problems with the Mercedes-Benz E350 as reported by actual vehicle owners. We'll tell you what the problem is and what it'll take to fix it.

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Known Problems

Vehicles equipped with a 7-speed automatic transmission may develop a rough shifting condition, most commonly going up from first to second gear and going down from third to second or second to first gear. Our technicians tell us this is due to an internal component failure. Mercedes has released updated parts; the transmission will need to be removed and disassembled to complete the necessary repairs.

The ESP and BAS warning lights may illuminate due to a failed brake light switch. Replacement of the failed switch should correct this concern.

High mileage or older vehicles commonly develop leaks from the differential seals and/or cover. Our technicians recommend a complete reseal of the differential unit whenever these leaks are repaired.

Due to the size and material used on the brakes of these vehicles, the brakes may start to squeak around the 50 percent wear point. The brake rotor surfaces become uneven, causing a lip to form at the outer edge of the rotor. Because of this, the rotors are usually replaced when the pads are worn (pad life varies depending on driving style and terrain).

The camshaft adjuster solenoid (which is related to the variable valve timing system) may fail or timing chain/balance shaft components may wear, resulting in illumination of the Check Engine Light and various drivability issues. Mercedes-Benz has released a service bulletin outlining specific repair instructions depending on fault codes stored.

The early versions of the central gateway module (which allows different systems to communicate with each other) have software problems. 

Irregular and premature tire wear can be caused by the front thrust link bushings cracking and causing excessive movement in the suspension. The thrust link bushings are fluid-filled (to help reduce vibration), so if they crack, they will leak oil.

Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.

This vehicle has sensotronic brake control (SBC). If the SBC light on the dash illuminates, have the brakes checked. If the SBC is not working, limited brake pressure is delivered to the front brakes, increasing the distance it takes to stop. The SBC hydraulic unit has a specific service life programmed into the control module; follow the manufacturer's recommended service procedure for proper maintenance of the SBC.

The engine may develop a stalling and/or no start condition due to a failed crankshaft position sensor.

Water can damage the weight sensor in the front, passenger seat, causing the SRS (airbag) light to illuminate. There is an electrical component in the seat cushion susceptible to fluid damage. Any spills should be dried up immediately in order to try and prevent damage to the sensor.

A vibration felt through the center floor of the vehicle can be caused by driveshaft flex discs, which crack and shred, causing excessive driveshaft movement. Not repairing these can cause damage to the driveshaft center support bearing, or, in the worst case scenario, damage to the transmission or differential.

Rear air springs (bellows) may develop leaks, which causes the air pump to run more often to maintain ride height. Our technicians recommend that leaking air springs be replaced.

A failed digital heater control valve can cause a lack of heat output from the climate control system.