If there is a vibration or noise at highway speed, it could be from the front driveshaft and may require replacement of the double cardan joint. A double cardan joint is a type of driveshaft joint that uses two universal joints.
Average mileage: 142,500 (35,000–250,000)
Drive Train affected: Automatic Transmission
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front double cardan u joints loose and front drive line loose
vibrates and rumbles at around 45mph when front drive shaft is engaged in 4x4 and in drive until truck is backed up to disengage front drive shaft.