Irregular and premature tire wear can be caused by the lower control arm bushings cracking, resulting excessive movement at the control arm pivot point. Ball joints can also wear out prematurely, causing similar tire wear symptoms. I some cases it may be necessary to replace the lower control arm, including bushings & ball joint to correct this concern.Google+
Car Problem Reports
Mercedes-Benz E320 4MATIC Premature Tire Wear Due to Cracked Lower Control Arm Bushings
Mercedes-Benz E320 4MATIC Problem
Average Mileage: 155,000 mi (110,000 mi - 200,000 mi)
Visitor, 2004 Mercedes-Benz E320 4MATIC
I had premature wear out of the front tires by 3 months after I bought this new car. The dealer said it was tire problem and not covered by the warranty. I bought new tires to replace the worn out tire. Four months later they called my car to replace something in the front tie-rod by the company.
Ball Joints went. but at 200K you can't be surprised.
Visitor, 2002 Mercedes-Benz E320 4MATIC, 110,000 mi
Irregular tire wear and groaning noise while going downhill and stopping. Mechanic wants to replace whole control arm not bushing. Any advice?