The power door lock actuators may become slow to operate or stop working completely and require replacement.Google+
Car Problem Reports
Cadillac Escalade Power Door Lock Actuators May Fail
Cadillac Escalade Problem
Average Mileage: 80,850 mi (11,000 mi - 200,000 mi)
Visitor, 2008 Cadillac Escalade, 55,000 mi
I also replaced the battery and shorly there after the rear door would not open. Then the front driver door would not lock. I have to go around the vec. to check all doors. What piece of CR__P. Wont ever buy a cadilac again
Visitor, 2008 Cadillac Escalade, 56,000 mi
Both rear doors lock actuators do not work on 2008 Cadillac Escalade ESV.
Visitor, 2004 Cadillac Escalade, 11,000 mi
Drivers side door power lock does not work.
Visitor, 2008 Cadillac Escalade, 93,000 mi
The door locks intermittently lock with key fob and sometimes do not unlock. It's very random. If you lock them all by hand, a different door or doors will unlock with the key fob.
Visitor, 2008 Cadillac Escalade, 95,000 mi
Driver side door lock does not work with remote or electronically inside vehicle. Also heated and cooled seats went out the same time. Dealers says it's over $1000 to repair these. BS!
Visitor, 2003 Cadillac Escalade, 100,000 mi
Right rear door actuator fails to lock the door.
Visitor, 2008 Cadillac Escalade, 37,000 mi
Power Door Lock Actuators Fail front p and rear driver side.
Visitor, 2008 Cadillac Escalade, 64,000 mi
Frony passenger door actuator started going out around 54000 miles. Already replaced rear right actuator and door handle.
Visitor, 2008 Cadillac Escalade, 70,000 mi
My rear lift gate won't 0pen automatically,I have to open lift gate manuallywhat's solutions .
Visitor, 2008 Cadillac Escalade, 82,000 mi
The same thing has happened to my car as well, the rear door lock has stopped working. It tries a couple times to open then quits. Sometimes can't even use manual open.