Overheating on 2001 Buick Regal

I have been having a problem with overheating... when the engine is running while parked its fine however as it starts to drive it overheats and cant seem to cool down thermostat was replaced not that water pump fine doesn't appear to be electrical... What could possibly be the problem... Please tell me good news..

Asked by for the 2001 Buick Regal
I would suspect a partially restricted radiator or a mildly blown head gasket. It may be wise to do a "block check". It is a chemical check that is quick and inexpensive to perform. It checks for the presence of carbon monoxide in the cooling system which would only be present if the head gasket was not sealing properly. I presume the cooling fan is working correctly.
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