The fuel pump may fail causing the engine to stall and not restart.
Car Problem Reports
Chevrolet Express 2500 "No start" Caused By Failed Fuel Pump
Chevrolet Express 2500 Problem
Engine Affected: 4.3L V6
Visitor, 2000 Chevrolet Express 2500, 4.3L V6, 159,000 mi
This van starts and will run fine, then it just decides not to start the next day. The fuel pump seems to be working fine. It was replaced as well as the computer. Any ideas why this thing only starts when it wants to?