The fuel injectors can fail and cause drivability problems. Often there is no Check Engine light and the failures can be caused by corrosion of the connector, clogging beyond the point of cleaning, and/or internal failures.
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Repairpal verified 2000 Nissan Xterra problems
The coolant outlet on the front of the lower intake manifold may develop a coolant leak.
The distributor shaft bearing can become rusty, and seize causing the engine to stall or not start. The failed distributor will commonly require replacement.