The EGR valve can become clogged with carbon, which causes the Check Engine Light to illuminate. This can result in moderate to severe misfires on acceleration and the EGR valve and passages will need to be cleaned.
Problems for specific Nissan Frontier years:
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Newest reported 2003 Nissan Frontier problems
The coolant outlet on the front of the lower intake manifold may develop a coolant leak.
A whining or buzzing type noise may develop from the timing chain area caused by excess slack in the secondary timing chains. Nissan has issued a service bulletin (NTB09-128) regarding this issue. Replacement of both secondary timing chains and their tensioner shoes will be necessary to repair this concern. As part of this repair, the engine oil and filter should also be replaced.
The distributor shaft bearing can become rusty, and seize causing the engine to stall or not start. The failed distributor will commonly require replacement.
About 3 months ago the right front control arm broke while I was pulling out of a parking lot and the right front wheel buckled under the truck. Yesterday the left front control arm broke while I was going at 45 mph. The left wheel blew out and the whole left front of the truck buckled. This truck has never carried heavy loads or been off road.