Hesitation - can be due to a vacuum leak, an air intake leak, a throttle body that needs cleaned, an EGR system issue, or a fuel pressure issue.
The best thing you can do preparing for a long trip is have a qualified technician evaluate the vehicle's condition. This will give you some insight as to what you may need to be prepared for.
Technical Service Bulletins help technicians diagnose "common" issues, but are not a listing of issues you can expect to have.
My suggestion is to review the vehicle page on RepairPal (http://repairpal.com/cars/gmc/rally+wagon+3500) and look at the common reported information there. It will give you some information that you can maybe use. Checking the vehicle is more important, overall, however. Good luck and safe travels!