The camshaft adjuster solenoid (which is related to the variable valve timing system) may fail or timing chain/balance shaft components may wear, resulting in illumination of the Check Engine Light and various drivability issues. Mercedes-Benz has released a service bulletin outlining specific repair instructions depending on fault codes stored.
2012 Mercedes-Benz S550 Problem Reports
Newest 2012 Mercedes-Benz S550 Problem Reports
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