Failed spark plug wires and/or ignition coils can cause intermittent misfires (rough running); the Check Engine Light may also illuminate. Diagnoses of the ignition system will be necessary to determine which components are at fault.
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Newest reported 1997 Mercedes-Benz E420 problems
Instrument cluster displays tend to fail, especially the clock and gear indicators; the instrument cluster needs to be replaced.
Irregular and premature tire wear can be caused by the lower control arm bushings cracking, resulting excessive movement at the control arm pivot point. Ball joints can also wear out prematurely, causing similar tire wear symptoms. I some cases it may be necessary to replace the lower control arm, including bushings & ball joint to correct this concern.
A squeak from the steering column is often related to a rubber boot in the column or a seal in the power steering rack.
The cooling system hoses may fail unexpectedly. The hoses can look good on the outside, but the rubber can degrade and erode on the inside. If not carefully checked, the hoses can burst at any time.
The switch for the vanity mirror light above the sun visor fail; there is an updated switch for some models. On the remaining models, due to a redesign, the mirror "cassette" will need replacement.
The electronic throttle assembly may suffer an electrical failure. It is often cheaper to send the valve to a service center for repair that to purchase a new part.
Brake lamp housings can melt, resulting in a loss of contact for the brake light bulb holder. If this happens, the brake light will not work. Replacement of the damaged lamp housing should correct this problem.
A coolant leak may develop form the Radiator due to degradation of its plastic components. Replacement of the failed radiator will be necessary.
High mileage vehicles may develop a leak from one or more of the transmission oil seals.
The emissions air injection pump can seize, causing a loud squealing noise followed by smoke from the drive belt. If the engine is not turned off, the belt will break, turning on the alternator/battery warning light.