Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.
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Newest reported 2011 Mercedes-Benz E350 problems
Vehicles equipped with a 7-speed automatic transmission may develop a rough shifting condition, most commonly going up from first to second gear and going down from third to second or second to first gear. Our technicians tell us this is due to an internal component failure. Mercedes has released updated parts; the transmission will need to be removed and disassembled to complete the necessary repairs.