Problems for specific Mercedes-Benz E320 years:
Car problem reports
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Newest reported 2004 Mercedes-Benz E320 problems
The check engine light illuminated. An OBD reader confirmed a problem with the Secondary Air Injection System. I also noticed a loud roaring type noise for the first two minutes after vehicle starting. The problem was traced to a failed Secondary Air Injection Air Pump. Dealer wanted $1,300 to replace. I sourced a Bosch pump for the application and replaced it myself for around $450.
Steering control arms are a fairly expensive replacement to have done - here in AZ all the rubber components perish before their expected time, causing erosion and damage that can only be fixed by full replacement. Next time you take your car in for routine maintenance, have them check over the front end to make sure that you're still in good shape
The crankshaft position sensor may fail. Symptoms of this are: The engine will crank—but not start—especially when the engine is warm. The car may start again if it is left to cool off, but it may run roughly or have poor performance.
The release tab for the center console can fall off unexpectedly.
Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.
Water can damage the weight sensor in the front, passenger seat, causing the SRS (airbag) light to illuminate. There is an electrical component in the seat cushion susceptible to fluid damage. Any spills should be dried up immediately in order to try and prevent damage to the sensor.
A failed digital heater control valve can cause a lack of heat output from the climate control system.
Due to exposure to the sun, lenses for head lights may become opaque (cloudy or hazy). This reduces the effectiveness of the lights. Our technicians tell us plastic polishes can improve the clarity of the lenses, but replacement of the lamp housings is the only way to regain the full intensity of the lights.
Irregular and premature tire wear can be caused by the front thrust link bushings cracking and causing excessive movement in the suspension. The thrust link bushings are fluid-filled (to help reduce vibration), so if they crack, they will leak oil.
The early versions of the central gateway module (which allows different systems to communicate with each other) have software problems.
Motor mounts commonly fail, causing engine vibrations to be transferred to the body. Failed motor mounts should be replaced in order to prevent damage to the transmission mount.
An engine Oil leak may develop from the PCV vent housing on the valve cover and/or the inspection plate on the front of the engine.