On higher mileage vehicles, an engine misfire may develop and/or the Check Engine Light may illuminate due to a failed ignition coil. It is not uncommon to replace all the coils when the first one fails in order to prevent return trips to the repair shop.
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Repairpal verified 2001 Lexus RX300 problems
The front suspension might make noise when going over bumps or rough roads. The support bushing for the suspension commonly needs to be replaced to correct this concern.
Debris can get into the idle air control valve. This will restrict the air flow into the engine, causing idle speed and/or stalling when cold. The valve can be cleaned or replaced to correct this concern.
Sludge can build up in the engine because Lexus did not recommend frequent enough oil changes. Lexus will sometimes offer a discount on cleaning the engine if necessary. Owners who changed their oil every 3,000 miles did not experience these problems. This sludge build up can lead to excessive oil consumption.