Misfire and/or Check Engine Light Due to Failed Ignition Coil on Lexus ES300

Problem Description and Possible Solution

On higher mileage vehicles, an engine misfire may develop and/or the Check Engine Light may illuminate due to a failed ignition coil. It is not uncommon to replace all the coils when the first one fails in order to prevent return trips to the repair shop.

Problem Data
RepairPal Verified
Average mileage: 155,065 (95,000–246,000)
12 model years affected: 1992, 1993, 1994, 1995, more1996, 1997, 1998, 1999, 2000, 2001, 2002, 2003
36 people reported this problem
Viewing 1 - 14 of 14 problem details
Check engine light blinking, loss of acceleration, smoke coming out from under hood; melted radiator reservoir; two rear coils replaced. Three days later, check engine light on solid, loss of acceleration. One more coil replaced. Two months later, misfire on #2. Replacing remaining three coils!
Ignition coil #5 failed
a miss fire was indicated by a code reader, cylinder number 2 coil was failing
Dash light on,engine miss fire.
Replace one coil,then another, then all of them with aftermarket Coils,bad idea.
Had to replace all again after six months with OEM parts. still ok after additional
40k.
The check engine light was on. I took it to Jerry Deluca's Auto Repair on Williams St., Staten Island. They told me the two front fuel ratio sensors needed to be replace for $610 including labor. He also recommended I change the spark plugs and ignition wires for another $300. He said it took 1 1/2 hrs diagnosing my problem and charged me $155 for diagnosis labor. A total of $1,065. Just to verify, I took it to the Shell Station Garage on Forest Avenue, Staten Island. They diagnosed it no charge and told me three ignition coils needed to be replaced. He said he would replace them and tune-up the car for $550. I went with the Shell Station Garage on Forest Avenue. I had to pay Jerry Deluca for the diagnosis labor to retrieve my car though.
Ignition Coil #5 failed
Same problems and symptoms, took to mechanic, computer did not register the failed coil though.
Mechanic swapped coils twice and identified the defective coil. Replaced two coils.
One year later more coils failed, will be repairing again...
I have the same problem on #2, bought the part and my mechanic can not locate where it belongs. Lexus told him the same place as his book states it will be but he can't find where the part goes, any help would be grealty appreciated
Check Engine Light is on since 127000 miles. Now, started today, after running for a while, CEL blinks for a minute and go off. It reappears after running 2-3 miles. Also, the car hesitates and runs sluggish.
Check engine light came on, went to pepboys. Im misfiring in the 1st, 2nd and 4th cylinders. Going to start with spark plugs and ohm testing to start. hope its not the expensive coil packs at $81 a piece.
sometimes it comes on and then goes off. Stays on most of the time
Check engine Light started blinking when engine was misfiring. The issue was probably due to an small manifold oil gasket oil leak. Four months later the Catalytic converter is clogged and needs to be replaced.
replaced coil for #2 cylinder. from reading the other comments, it sounds like I may be replacing the other ones soon.
replaced 1 ignition coil