Howling droan coming from rear each time its driven. on 2010 Mazda Mazda5

Droaning appears to come from rear,& intensifies with speed.Sounds like rear end diff. is going if it had one.Back tires are 60% with wear showing on insides of both.Could it be the tires?

Asked by for the 2010 Mazda Mazda5
Yes; tires with abnormal wear patters can really resonate noise.

Also have a look at the vehicle wheel bearings.