How to replace the spark plugs? on 2007 Lexus RX400h

My car is approaching 100,000 miles, so I would like to replace the spark plugs. Any helpful tips n how to access the spark plugs for removal and replacement is appeciated.

Asked by for the 2007 Lexus RX400h
if you trace the wires (6) YOU'LL FIND THE PLUGS.... many times it's easier and faster to remove anything in the way than it is to do Mechanic Yoga, reach around.... seems like more work but often easier and faster.

when re-inserting, turn plug COUNTER-CLOCKWISE till you feel it CLICK to verify thread allignment, then tighten by hand and finish with socket wrench (1/16th turn).