The AC compressor may seize resulting in loss of cold air from the AC vents. Often when the compressor fails in the fashion, debris is spread through out the entire air conditioning system resulting in very expensive repairs.
Problems for specific Honda CR-V years:
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Newest reported 2012 Honda CR-V problems
The front brake rotors can warp and cause a vibration when braking. The rotors will need to be machined or in cases where they are worn to thin, replaced to correct this issue.