Ford has a manufacturing defect in the assembly of the body panels. The inner fender well and outside body panel area is filled with a solid foam insulation in an effort to avoid metal to metal contact. The foam material retains moisture causing premature failure of the interior wheel arch support as well as the exterior body panel. The repair is costly as it requires the removal of the rusted sheet metal and fabrication and welding in new so...
Problems for specific Ford F-350 Super Duty years:
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Newest reported 2002 Ford F-350 Super Duty problems
A severe lack of power may develop because the hose from the turbocharger to the intake manifold can come loose, resulting in loss of boost pressure to the engine.
There is a technical service bulletin for the V8 engines regarding a possible problem with the spark plug being ejected from the cylinder head, damaging the threads in the spark plug hole. If the vehicle is under warranty, cylinder head replacement is recommended. If the vehicle is out of warranty, Ford authorized the use of a specific thread insert to repair the head.