It is important to check the air filter maintenance minder periodically and service the air filter when recommended. The air filter minder monitors the vacuum in the intake and vacuum builds as the filter gets plugged. Vacuum can build enough so that it draws oil through the seals inside the turbocharger, damaging the seals.
Problems for specific Ford F-350 Super Duty years:
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Newest reported 2000 Ford F-350 Super Duty problems
There is a technical service bulletin for the V8 engines regarding a possible problem with the spark plug being ejected from the cylinder head, damaging the threads in the spark plug hole. If the vehicle is under warranty, cylinder head replacement is recommended. If the vehicle is out of warranty, Ford authorized the use of a specific thread insert to repair the head.