Engine Skipping on 1992 Mercedes-Benz 500E

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My 500 E misses severely to the point that it is now hard to get going when it is not driven for a few days. Initially, it runs OK, but if parked and then restarted, it misses severely. If I drive it daily, it runs smoothly. I have had the plug wires and plugs changed. It acts like it is not getting air or ? fuel. ? computer problem?

(1) Answer
Do you have electronic fuel injection? Or are the injectors mechanical? If they're mechanical, check for vacuum leaks. A vacuum leak will cause all sorts of issues. Sounds like a possible fuel supply issue too, so you may want to find a good Mercedes tech and have them look it over.