The crankshaft position sensor may fail. Symptoms of this are: The engine will crank—but not start—especially when the engine is warm. The car may start again if it is left to cool off, but it may run roughly or have poor performance.Google+
Car Problem Reports
Mercedes-Benz E430 Engine Performance Problems Due to Crankshaft Position Sensor Failure
Mercedes-Benz E430 Problem
Average Mileage: 129,546 mi (60,222 mi - 183,000 mi)
Visitor, 2000 Mercedes-Benz E430, 150,000 mi
Had to replace it did not know it was a common prolem..had 1999 E320 never but the E430 year 2000 within six month after I bought it as used from a dealerin 2012
Visitor, 2001 Mercedes-Benz E430, 126,700 mi
same as described, had to have it towed of MB dealer to be replaced
Visitor, 2001 Mercedes-Benz E430, 120,000 mi
Stopped at a red light...Turned Green car died. Wouldnt restart...2 men pushed my car to a nearby parking lot. Later that evening it did start after it had cooled off.
Visitor, 2000 Mercedes-Benz E430, 126,000 mi
Had towed and repaired at Millenium Mercedes (Now Open Road)
Visitor, 1998 Mercedes-Benz E430, 60,222 mi
Dies when warm when at a stop. When cools off it starts.
Visitor, 2002 Mercedes-Benz E430, 147,000 mi
Afternoon, 4xcrank, walked away 30 minutes, then worked. Worked later that afternoon 1st crank. Next morning, 16xcrank, jumper battery, unhook cables, 4xcrank and it started. Drove straight to MB shop to fix. Used toyota from collegiate son on break. Shop fixed MB next day. Probably never purchase an MB again.
Visitor, 2001 Mercedes-Benz E430, 183,000 mi
engine cranks but will not start. After an hour or so it starts and continues to start even if hot. It has been suggested that the fuel filter may be old and needs to be replaced. This starting problem has only happened three times in the last year. The check engine light also came on when I did get the car started.