engine missfire cylinder 1 on 2000 Chevrolet Venture

idling rough will not accelerate and code from handheld is po301

Asked by for the 2000 Chevrolet Venture
Check the spark plug for that cylinder ASAP as well as all the ignition wires etc.
1 more answer
I would suggest you being by checking the number 1 cylinder ignition and spark plug and the #1 and #4 spark plug wires. After that diagnosing your engine misfire becomes more difficult.