engine misfire sometimes on 1994 Chevrolet S10

Rookie cbe0621eac06868b3efe0d8d1d3611e23c60d3114864ea2ec19a68cfbd3eebab
misfires sometimes at idle and also at acceleration ,but clears up on highway driving over 50 mph
(1) Answer
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It could be many things, unfortunately and without experiencing the problem first hand or being able to do some basic diagnostic tests its hard to say. It could be an ignition failure (bad spark plug plug wires ect...) could be fuel system related or a vacuum leak ect.....
I did have a strange problem with of these that had bad valve springs causing a misfire, a friend that works on Chevys said he had seen that before on an S10.