drivability issue on 2007 Chevrolet Uplander

my 2007 chevy uplander has a drivabilty issue. sometimes while driving the passenger side wheel will lock up. what woould cause this to happen. now i'm starting to have problems with the transmission.

Asked by for the 2007 Chevrolet Uplander
That's a tough one. If it locks up when you touch the brake, there may be a brake problem, if the thing just locks up anytime, it's a mystery to me. Get it towed to a Chevy specialist ASAP, sounds like a safety issue.
If you want to find a specialist, here's a directory link for you: