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drivability issue on 2007 Chevrolet Uplander

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my 2007 chevy uplander has a drivabilty issue. sometimes while driving the passenger side wheel will lock up. what woould cause this to happen. now i'm starting to have problems with the transmission.
(1) Answer
That's a tough one. If it locks up when you touch the brake, there may be a brake problem, if the thing just locks up anytime, it's a mystery to me. Get it towed to a Chevy specialist ASAP, sounds like a safety issue.
If you want to find a specialist, here's a directory link for you:
https://repairpal.com/directory?address=85222&car_brand_names=Chevrolet