The door for the vanity mirror (or the frame for the door) can break; due to a redesign, the mirror "cassette" will need replacement.
Resources for the Repair and Maintenance of your 2005 Mercedes-Benz S500 4MATIC
2005 Mercedes-Benz S500 4MATIC
2005 Mercedes-Benz S500 4MATIC Problems
The relay which turns the airmatic suspension pump on may fail causing the pump to run continuously. This can result in failure of the pump motor or a dead battery as the pump motor will continue to run after the car is turned off. Also, Worn airmatic pump mount bushings can causes noises in the front axle while driving on bumpy roads or a buzzing noise while the pump is running.
A door control module/actuator may fail. Our technicians recommend finding an expert to repair them. Taking the door trim panels off requires expert knowledge because they can break and the pieces are very expensive.
The center console armrest can break. Replacement is commonly the recommended repair.
Front thrust arm and control arm bushings can crack and sometimes tear completely. If this is not repaired quickly, damage to the front subframe unit will occur, which is very expensive to repair. Updated control arms (that prevent damage to the subframe when the bushings wear out) are available.
2005 Mercedes-Benz S500 4MATIC Questions and Answers
How often is it necessery to flush/replace the power steering fluid?
I am trying to retract the calipers to replace front rotors, brake pads and sensor. I wanted to make sure no errors comeup when I do this and I dont want to lose my fingers due to the caliper crush...
please describe how to replace a faulty elements
cant shift out from parking. can not drive at all
when I use my automatic key to lock the doors fog lights flash, alarms are going off not sure what's happening.