2006 Mercedes-Benz E350 Repair and Maintenance

A guide to problems, costs, maintenance and repair for your 2006 Mercedes-Benz E350

2006 Mercedes-Benz E350 Problems

Internal Component Failure May Cause Rough Shifting

Vehicles equipped with a 7-speed automatic transmission may develop a rough shifting condition, most commonly going up from first to second gear and going down from third to second or second to first gear. Our technicians tell us this is due to an internal component failure. Mercedes has released updated parts; the transmission will need to be removed and disassembled to complete the necessary repairs.

Failed Gateway Module May Cause Lack of Audio/Cell Phone Functionality

Lack of audio or cell phone functionality may be related to the failure of the audio gateway module.

Cracked Driveshaft Flex Discs May Cause Driveshaft Movement/Vibration

A vibration felt through the center floor of the vehicle can be caused by driveshaft flex discs, which crack and shred, causing excessive driveshaft movement. Not repairing these can cause damage to the driveshaft center support bearing, or, in the worst case scenario, damage to the transmission or differential.

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2006 Mercedes-Benz E350 Recalls

Incorrect Software Calibration May Cause Fuel Pump to Remain Powered in a Collision

There is a faulty software calibration that affects several areas including shutting off the fuel supply in a collision. This could cause a fire hazard during an accident. Dealers will reprogram this software. The Mercedes-Benz recall number is 2008 070001. This recall began during August, 2008.

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2006 Mercedes-Benz E350 Reviews

This is an awesome car that I was very pleased with when I bought it. Added the iPod cable and a Bluetooth pod to the car and it works very well. However, the CD Changer. I expected more from Mercedes-Benz on this one. So, a CD is stuck in the Changer and when I took it to the dealer to have it removed, they said the ONLY option was to purchase a new CD Changer for $ 995.00. I was kind of shock...
Purchased 2006 E350 with 55K miles in 2009. Loved the ride and the handling. Great car for my sales job. At 110K miles in 2011, car began to shimmy on a cold start. In later weeks, the car would shake violently on start up. Was told that it was a "balance shaft rotor", a small part about the size of a lipstick case deep inside the engine. Apparently for 2006 and other similar years this part wa...
Bought car brand new in 2005. Have the same issue as others with Engine Check light due to balance shaft gear wear, requiring pulling the engine and replacing the balance shaft - at a cost of about $5500.

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