could this be a bad engine mount or transmission problem?
Car shaking when going uphill? on 2000 Acura TL
Could be an EGR problem causing a lean condition/ all the EGR gasses being allocated to only a few cylinders (common Acura problem) or a failed ignition coil but needs to be properly checked out.
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A diagnostic check is needed....try my shop...call 973-483-4489