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Q:

Car runs fine when first start up then after aprox 5mins cylinder number 5 dies on 1990 Nissan 300ZX

Rookie cbe0621eac06868b3efe0d8d1d3611e23c60d3114864ea2ec19a68cfbd3eebab
And has no reasponse at all Have changed coil packs and plugs and no change what could be causing this.
(2) Answers
You are missing 'what' #5 is missing 'when' #5 is missing....if you figure this out,, problem solved! Let a mechanic help you out...hands-on.
Got milk........er , I mean , fuel? Weak injector? Expensive guess, or follow suggestion #1. Might save a lot of time money and aggravation!