The fuel pump may fail causing the engine to stall and not restart.
Car problem reports
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Most reported 2008 Buick Lucerne problems
A Loose or worn gas cap may cause Check Engine Light to illuminate.
The engine may develop an oil leak from the lower crankcase portion of the engine block. Our technicians tell us that the engine must be removed from the vehicle to properly repair this oil leak.
An intake manifold vacuum leak can develop from a variety of sources, often causing illumination of the Check Engine Light with codes P0171 & P0174 stored. Thorough diagnoses will be necessary to pinpoint the cause in order to make the correct repairs. A "smoke" machine is often used to isolate the cause of difficult to find vacuum leaks.
The front struts may show signs of wear, or be excessively bouncy ride at freeway speeds. This may begin to occur at around 75,000 miles.
The steering wheel position sensor may fail, resulting in the service stability message being displayed.
Car would begin to misfire, run rough, and stall after being driven for awhile. Sometimes door locks would chatter or other odd electrical problems. Poor connection of main harness into distribution box beneath the back seat. Replace connector and distribution box. Warning: Unburnt fuel in exhaust from initial problem will lead to catalytic converter failure.