Best way to describe the problem is it acts like it has bad fuel/water in gas. on 2002 Honda CR-V

For no reason from time to time when i get to 2600 on the tac it will start to choke out like it has bad fuel or water in the fuel. I run shell or quality gas and use lucas additives. We have replaced the 02sensors and it will run fine for awhile then all of a sudden it spits and sputters loosing power. The harder you press on the gas peddle the slower it will go and the harder it shakes and kicks.

1 answer
Is the check engine lamp on? There are many possibilities. I would start out by scanning the computer and checking the signals while you are driving it.