Best way to describe the problem is it acts like it has bad fuel/water in gas. on 2002 Honda CR-V

For no reason from time to time when i get to 2600 on the tac it will start to choke out like it has bad fuel or water in the fuel. I run shell or quality gas and use lucas additives. We have replaced the 02sensors and it will run fine for awhile then all of a sudden it spits and sputters loosing power. The harder you press on the gas peddle the slower it will go and the harder it shakes and kicks.

Asked by for the 2002 Honda CR-V
Is the check engine lamp on? There are many possibilities. I would start out by scanning the computer and checking the signals while you are driving it.
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